Effects of neurofeedback on the activities of motor-related areas by using motor execution and imagery

Previous studies have reported that real-time functional magnetic resonance imaging (fMRI) neurofeedback using motor imagery can modulate the activity of several motor-related areas. However, differences in these modulatory effects on distinct target regions same experimental protocol remain unelucidated. This study aimed to compare primary area (M1) and ventral premotor cortex (PMv). Of included participants, 15 received blood oxygenation level-dependent (BOLD) signals from their left M1, other PMv. Both groups were instructed try increase score (NF-Score), which reflected averaged activation level region, by executing or imagining a right-hand clenching movement. The result revealed during condition, M1 was deactivated PMv-group but not M1-group, whereas PMv activated M1-group. Our finding indicates has different brain regulation.